Loss of Cystic Fibrosis Transmembrane Conductance Regulator Function Produces Abnormalities in Tracheal Development in Neonatal Pigs and Young Children

Rationale: Although airway abnormalities are common in patients with cystic fibrosis (CF), it is unknown whether they are all secondary to postnatal infection and inflammation, which characterize the disease. Objectives: To learn whether loss of the cystic fibrosis transmembrane conductance regulato...

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Detalhes bibliográficos
Main Authors: Meyerholz, David K., Stoltz, David A., Namati, Eman, Ramachandran, Shyam, Pezzulo, Alejandro A., Smith, Amanda R., Rector, Michael V., Suter, Melissa J., Kao, Simon, McLennan, Geoffrey, Tearney, Guillermo J., Zabner, Joseph, McCray, Paul B., Welsh, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
C. Cystic Fibrosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001264/
https://ncbi.nlm.nih.gov/pubmed/20622026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201004-0643OC
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