The Regulatory Mechanism of Extracellular Hsp90α on Matrix Metalloproteinase-2 Processing and Tumor Angiogenesis

Heat shock protein 90α (Hsp90α) is a ubiquitously expressed molecular chaperone that is essential for eukaryotic homeostasis. Hsp90α can also be secreted extracellularly, where it has been shown to be involved in tumor metastasis. Extracellular Hsp90α interacts with and promotes the proteolytic acti...

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Hlavní autoři: Song, Xiaomin, Wang, Xiaofeng, Zhuo, Wei, Shi, Hubing, Feng, Dan, Sun, Yi, Liang, Yun, Fu, Yan, Zhou, Daifu, Luo, Yongzhang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000986/
https://ncbi.nlm.nih.gov/pubmed/20937816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181941
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