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The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy
Heat shock protein 90-α (Hsp90α) is an intracellular molecular chaperone. However, it can also be secreted with the underlying regulatory mechanism remaining far from clear. Here we show that the secreted Hsp90α is a C-terminal truncated form and its secretion is regulated by the C-terminal EEVD mot...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795546/ https://ncbi.nlm.nih.gov/pubmed/19965370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908151106 |
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