The Regulatory Mechanism of Extracellular Hsp90α on Matrix Metalloproteinase-2 Processing and Tumor Angiogenesis

Heat shock protein 90α (Hsp90α) is a ubiquitously expressed molecular chaperone that is essential for eukaryotic homeostasis. Hsp90α can also be secreted extracellularly, where it has been shown to be involved in tumor metastasis. Extracellular Hsp90α interacts with and promotes the proteolytic acti...

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Autores principales: Song, Xiaomin, Wang, Xiaofeng, Zhuo, Wei, Shi, Hubing, Feng, Dan, Sun, Yi, Liang, Yun, Fu, Yan, Zhou, Daifu, Luo, Yongzhang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000986/
https://ncbi.nlm.nih.gov/pubmed/20937816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181941
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