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Dioxygenase Activity of Epidermal Lipoxygenase-3 Unveiled: TYPICAL AND ATYPICAL FEATURES OF ITS CATALYTIC ACTIVITY WITH NATURAL AND SYNTHETIC POLYUNSATURATED FATTY ACIDS

Epidermal lipoxygenase-3 (eLOX3) exhibits hydroperoxide isomerase activity implicated in epidermal barrier formation, but its potential dioxygenase activity has remained elusive. We identified herein a synthetic fatty acid, 9E,11Z,14Z-20:3ω6, that was oxygenated by eLOX3 specifically to the 9S-hydro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Yuxiang, Brash, Alan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000968/
https://ncbi.nlm.nih.gov/pubmed/20921226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155374
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