Rod phosphodiesterase-6 PDE6A and PDE6B Subunits Are Enzymatically Equivalent

Phosphodiesterase-6 (PDE6) is the key effector enzyme of the phototransduction cascade in rods and cones. The catalytic core of rod PDE6 is a unique heterodimer of PDE6A and PDE6B catalytic subunits. The functional significance of rod PDE6 heterodimerization and conserved differences between PDE6AB...

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Autores principales: Muradov, Hakim, Boyd, Kimberly K., Artemyev, Nikolai O.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000964/
https://ncbi.nlm.nih.gov/pubmed/20940301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170068
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