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Cyclotides, a promising molecular scaffold for peptide-based therapeutics

Cyclotides are a new emerging family of large plant-derived backbone-cyclized polypeptides (≈30 amino acids long) that share a disulfide-stabilized core (3 disulfide bonds) characterized by an unusual knotted structure. Their unique circular backbone topology and knotted arrangement of three disulfi...

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Bibliografische gegevens
Hoofdauteurs: Jagadish, Krishnappa, Camarero, Julio A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000894/
https://ncbi.nlm.nih.gov/pubmed/20564025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21433
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