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Cyclotides, a promising molecular scaffold for peptide-based therapeutics
Cyclotides are a new emerging family of large plant-derived backbone-cyclized polypeptides (≈30 amino acids long) that share a disulfide-stabilized core (3 disulfide bonds) characterized by an unusual knotted structure. Their unique circular backbone topology and knotted arrangement of three disulfi...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000894/ https://ncbi.nlm.nih.gov/pubmed/20564025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21433 |
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