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Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels

PURPOSE: Antibodies form an important class of cancer therapeutics, and there is intense interest in using them for imaging applications in diagnosis and monitoring of cancer treatment. Despite the expanding body of knowledge describing pharmacokinetic and pharmacodynamic interactions of antibodies...

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Detalhes bibliográficos
Main Authors: Thurber, Greg M., Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000888/
https://ncbi.nlm.nih.gov/pubmed/20809210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0397-7
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