SYSTEMIC INFLAMMATION AND LIVER INJURY FOLLOWING HEMORRHAGIC SHOCK AND PERIPHERAL TISSUE TRAUMA INVOLVE FUNCTIONAL TLR9 SIGNALING ON BONE MARROW-DERIVED CELLS AND PARENCHYMAL CELLS

Hemorrhagic shock due to trauma (HS/T) induces an inflammatory response that can contribute to end-organ injury. The pathways involved in the initiation and propagation of HS/T-induced inflammation are incompletely understood. Here, we hypothesized that the DNA sensor TLR9 would have a role in infla...

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Hauptverfasser: Gill, Roop, Ruan, Xiangcai, Menzel, Christoph J., Namkoong, Seung, Loughran, Patricia, Hackam, David J, Billiar, Timothy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000874/
https://ncbi.nlm.nih.gov/pubmed/20577143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181eddcab
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