TLR2 on bone marrow and non-bone marrow derived cells regulates inflammation and organ injury in cooperation with TLR4 during resuscitated hemorrhagic shock

BACKGROUND: Although the role of TLR4 in driving inflammation and organ injury after hemorrhagic shock and resuscitation (H/R) is well established, the role of TLR2 - another receptor for damage-associated molecular pattern (DAMP) molecules - is not. In this study, we used a combination of TLR2(−/−)...

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Vydáno v:Shock
Hlavní autoři: Korff, Sebastian, Loughran, Patricia, Cai, Changchun, Fan, Jie, Elson, Greg, Shang, Limin, Pires, Susana Salgado, Lee, Yi Shan, Guardado, Jesse, Scott, Melanie, Billiar, Timothy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069107/
https://ncbi.nlm.nih.gov/pubmed/27172151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000650
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