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Kita Driven Expression of Oncogenic HRAS Leads to Early Onset and Highly Penetrant Melanoma in Zebrafish

BACKGROUND: Melanoma is the most aggressive and lethal form of skin cancer. Because of the increasing incidence and high lethality of melanoma, animal models for continuously observing melanoma formation and progression as well as for testing pharmacological agents are needed. METHODOLOGY AND PRINCI...

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Bibliografiske detaljer
Main Authors: Santoriello, Cristina, Gennaro, Elisa, Anelli, Viviana, Distel, Martin, Kelly, Amanda, Köster, Reinhard W., Hurlstone, Adam, Mione, Marina
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000817/
https://ncbi.nlm.nih.gov/pubmed/21170325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015170
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