Kita Driven Expression of Oncogenic HRAS Leads to Early Onset and Highly Penetrant Melanoma in Zebrafish

BACKGROUND: Melanoma is the most aggressive and lethal form of skin cancer. Because of the increasing incidence and high lethality of melanoma, animal models for continuously observing melanoma formation and progression as well as for testing pharmacological agents are needed. METHODOLOGY AND PRINCI...

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Main Authors: Santoriello, Cristina, Gennaro, Elisa, Anelli, Viviana, Distel, Martin, Kelly, Amanda, Köster, Reinhard W., Hurlstone, Adam, Mione, Marina
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000817/
https://ncbi.nlm.nih.gov/pubmed/21170325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015170
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