Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB

BACKGROUND: Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human malignancies, especially the androgen-independent prostate cancer (AIPC) with constitutive NF-κB activation. Celastrol induces apoptosis by means of proteasome inhibition and suppresses prosta...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dai, Yao, DeSano, Jeffrey, Tang, Wenhua, Meng, Xiaojie, Meng, Yang, Burstein, Ezra, Lawrence, Theodore S., Xu, Liang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000808/
https://ncbi.nlm.nih.gov/pubmed/21170316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014153
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak