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Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery

DNA methylation is an epigenetic mark critical for regulating transcription, chromatin structure and genome stability. Although many studies have shed light on how methylation impacts transcription and interfaces with the histone code, far less is known about how it regulates genome stability. We an...

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Main Authors: Ha, Kyungsoo, Lee, Gun Eui, Palii, Stela S., Brown, Kevin D., Takeda, Yoshihiko, Liu, Kebin, Bhalla, Kapil N., Robertson, Keith D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000680/
https://ncbi.nlm.nih.gov/pubmed/20940144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq451
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