Chronic heart failure decreases cross-bridge kinetics in single skeletal muscle fibres from humans

Skeletal muscle function is impaired in heart failure patients due, in part, to loss of myofibrillar protein content, in particular myosin. In the present study, we utilized small-amplitude sinusoidal analysis for the first time in single human skeletal muscle fibres to measure muscle mechanics, inc...

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Bibliografiske detaljer
Main Authors: Miller, Mark S, VanBuren, Peter, LeWinter, Martin M, Braddock, Joan M, Ades, Philip A, Maughan, David W, Palmer, Bradley M, Toth, Michael J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2010
Fag:
Skeletal Muscle and Exercise
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000591/
https://ncbi.nlm.nih.gov/pubmed/20724360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191957
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