Chronic heart failure decreases cross-bridge kinetics in single skeletal muscle fibres from humans

Skeletal muscle function is impaired in heart failure patients due, in part, to loss of myofibrillar protein content, in particular myosin. In the present study, we utilized small-amplitude sinusoidal analysis for the first time in single human skeletal muscle fibres to measure muscle mechanics, inc...

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Detalhes bibliográficos
Main Authors: Miller, Mark S, VanBuren, Peter, LeWinter, Martin M, Braddock, Joan M, Ades, Philip A, Maughan, David W, Palmer, Bradley M, Toth, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Skeletal Muscle and Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000591/
https://ncbi.nlm.nih.gov/pubmed/20724360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191957
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