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DNA search efficiency is modulated by charge composition and distribution in the intrinsically disordered tail
Intrinsically disordered tails are common in DNA-binding proteins and can affect their search efficiency on nonspecific DNA by promoting the brachiation dynamics of intersegment transfer. During brachiation, the protein jumps between distant DNA regions via an intermediate state in which the tail an...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000266/ https://ncbi.nlm.nih.gov/pubmed/21078959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011775107 |
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