Paradoxical effects of constitutive human IL-32γ in transgenic mice during experimental colitis

Inflammatory cytokines mediate inflammatory bowel diseases (IBDs) and cytokine blocking therapies often ameliorate the disease severity. IL-32 affects inflammation by increasing the production of IL-1, TNFα, and several chemokines. Here, we investigated the role of IL-32 in intestinal inflammation b...

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Autors principals: Choi, Jida, Bae, Suyoung, Hong, Jaewoo, Ryoo, Soyoon, Jhun, Hyunjhung, Hong, Kwangwon, Yoon, Doyoung, Lee, Siyoung, Her, Erk, Choi, Wonhyuk, Kim, Jeonghwan, Azam, Tania, Dinarello, Charles A., Kim, Soohyun
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000248/
https://ncbi.nlm.nih.gov/pubmed/21078994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015418107
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