RNA channelling by the eukaryotic exosome

The eukaryotic exosome is a key nuclease for the degradation, processing and quality control of a wide variety of RNAs. Here, we report electron microscopic reconstructions and pseudo-atomic models of the ten-subunit Saccharomyces cerevisiae exosome in the unbound and RNA-bound states. In the RNA-bo...

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Bibliografiske detaljer
Main Authors: Malet, Hélène, Topf, Maya, Clare, Daniel K, Ebert, Judith, Bonneau, Fabien, Basquin, Jerome, Drazkowska, Karolina, Tomecki, Rafal, Dziembowski, Andrzej, Conti, Elena, Saibil, Helen R, Lorentzen, Esben
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999861/
https://ncbi.nlm.nih.gov/pubmed/21072061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.164
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