Eksport udført — 

Pleiotropic effects of the lpxM mutation in Yersinia pestis resulting in modification of the biosynthesis of major immunoreactive antigens

Deletion mutants in the lpxM gene in two Y. pestis strains, the live Russian vaccine strain EV NIIEG and a fully virulent strain, 231, synthesise a less toxic penta-acylated lipopolysaccharide (LPS). Analysis of these mutants revealed they possessed marked reductions in expression and immunoreactivi...

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Bibliografiske detaljer
Main Authors: Feodorova, V.A., Pan'kina, L.N., Savostina, E.P., Kuznetsov, O.S., Konnov, N.P., Sayapina, L.V., Dentovskaya, S.V., Shaikhutdinova, R.Z., Ageev, S.A., Lindner, B., A.N.Kondakova, Bystrova, O.V., Kocharova, N.A., Senchenkova, S.N., Holst, O., Pier, G.B., Knirel, Y.A., Anisimov, A.P., Motin, V.L.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999740/
https://ncbi.nlm.nih.gov/pubmed/19428838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.02.020
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