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Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer

BACKGROUND: Conflicting data exist regarding the prognostic and predictive impact of survivin (BIRC5) in breast cancer. We previously reported survivin cytoplasmic-to-nuclear ratio (CNR) as an independent prognostic indicator in breast cancer. Here, we validate survivin CNR in a separate and extende...

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Detalhes bibliográficos
Main Authors: Rexhepaj, Elton, Jirstrom, Karin, O'Connor, Darran P, O'Brien, Sallyann L, Landberg, Goran, Duffy, Michael J, Brennan, Donal J, Gallagher, William M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999619/
https://ncbi.nlm.nih.gov/pubmed/21092276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-639
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