Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

INTRODUCTION: Manual interpretation of immunohistochemistry (IHC) is a subjective, time-consuming and variable process, with an inherent intra-observer and inter-observer variability. Automated image analysis approaches offer the possibility of developing rapid, uniform indicators of IHC staining. I...

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Detalhes bibliográficos
Main Authors: Rexhepaj, Elton, Brennan, Donal J, Holloway, Peter, Kay, Elaine W, McCann, Amanda H, Landberg, Goran, Duffy, Michael J, Jirstrom, Karin, Gallagher, William M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614526/
https://ncbi.nlm.nih.gov/pubmed/18947395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2187
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