Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

The DEAD box helicase DDX3 assembles IPS-1 (also called Cardif, MAVS, or VISA) in non-infected human cells where minimal amounts of the RIG-I-like receptor (RLR) protein are expressed. DDX3 C-terminal regions directly bind the IPS-1 CARD-like domain as well as the N-terminal hepatitis C virus (HCV)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Oshiumi, Hiroyuki, Ikeda, Masanori, Matsumoto, Misako, Watanabe, Ayako, Takeuchi, Osamu, Akira, Shizuo, Kato, Nobuyuki, Shimotohno, Kunitada, Seya, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999533/
https://ncbi.nlm.nih.gov/pubmed/21170385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014258
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados