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Myeloid-Derived Suppressor Cells Confer Tumor-Suppressive Functions on Natural Killer Cells via Polyinosinic: Polycytidylic Acid Treatment in Mouse Tumor Models

Polyinosinic:polycytidylic acid (poly I:C), a synthetic double-stranded RNA, acts on myeloid cells and induces potent antitumor immune responses including natural killer (NK) cell activation. Myeloid-derived suppressor cells (MDSCs) systemically exist in tumor-bearing hosts and have strong immunosup...

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Bibliografiske detaljer
Udgivet i:J Innate Immun
Main Authors: Shime, Hiroaki, Kojima, Ayako, Maruyama, Akira, Saito, Yusuke, Oshiumi, Hiroyuki, Matsumoto, Misako, Seya, Tsukasa
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741616/
https://ncbi.nlm.nih.gov/pubmed/24192491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355126
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