Inhibition of the Type 2 Iodothyronine Deiodinase Underlies the Elevated Plasma TSH Associated with Amiodarone Treatment

The widely prescribed cardiac antiarrhythmic drug amiodarone (AMIO) and its main metabolite, desethylamiodarone (DEA), have multiple side effects on thyroid economy, including an elevation in serum TSH levels. To study the AMIO effect on TSH, mice with targeted disruption of the type 2 deiodinase ge...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Rosene, Matthew L., Wittmann, Gábor, Arrojo e Drigo, Rafael, Singru, Praful S., Lechan, Ronald M., Bianco, Antonio C.
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999495/
https://ncbi.nlm.nih.gov/pubmed/20926587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0553
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki