Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: Implications for HIV-1 vaccine development

Passive transfer of high-titered antiviral neutralizing IgG, known to confer sterilizing immunity in pig-tailed monkeys, has been used to determine how soon after virus exposure neutralizing antibodies (NAbs) must be present to block a simian immunodeficiency virus (SIV)/HIV chimeric virus infection...

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Hlavní autoři: Nishimura, Yoshiaki, Igarashi, Tatsuhiko, Haigwood, Nancy L., Sadjadpour, Reza, Donau, Olivia K., Buckler, Charles, Plishka, Ron J., Buckler-White, Alicia, Martin, Malcolm A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC299920/
https://ncbi.nlm.nih.gov/pubmed/14627745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2436476100
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