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Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast
The repair of chromosomal double-strand breaks (DSBs) can be accomplished through homologous recombination in most organisms. We report here that exogenous oligonucleotides can efficiently target for repair a single DSB induced in a chromosome of yeast. The efficiency of recombinational targeting le...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299876/ https://ncbi.nlm.nih.gov/pubmed/14630945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036296100 |
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