Chromosomal site-specific double-strand breaks are efficiently targeted for repair by oligonucleotides in yeast
The repair of chromosomal double-strand breaks (DSBs) can be accomplished through homologous recombination in most organisms. We report here that exogenous oligonucleotides can efficiently target for repair a single DSB induced in a chromosome of yeast. The efficiency of recombinational targeting le...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
2003
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299876/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14630945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2036296100 |
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