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Conservative Repair of a Chromosomal Double-Strand Break by Single-Strand DNA through Two Steps of Annealing

The repair of chromosomal double-strand breaks (DSBs) is essential to normal cell growth, and homologous recombination is a universal process for DSB repair. We explored DSB repair mechanisms in the yeast Saccharomyces cerevisiae using single-strand oligonucleotides with homology to both sides of a...

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Autori principali: Storici, Francesca, Snipe, Joyce R., Chan, Godwin K., Gordenin, Dmitry A., Resnick, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636868/
https://ncbi.nlm.nih.gov/pubmed/16908537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00672-06
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