Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis

Base excision repair (BER) provides relief from many DNA lesions. While BER enzymes have been characterized biochemically, BER functions within cells are much less understood, in part because replication bypass and double-strand break (DSB) repair can also impact resistance to base damage. To invest...

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Hlavní autoři: Ma, Wenjian, Resnick, Michael A., Gordenin, Dmitry A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346603/
https://ncbi.nlm.nih.gov/pubmed/18267974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1148
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