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Targeted Delivery of siRNA to Hepatocytes and Hepatic Stellate Cells by Bioconjugation
Previously, we successfully conjugated galactosylated poly(ethylene glycol) (Gal-PEG) to oligonucleotides (ODNs) via an acid labile ester linker (Zhu et al., Bioconjug Chem, 2008, 19: 290-8). In this study, antisense strands of siRNA were conjugated to Gal-PEG and mannose 6-phosphate poly(ethylene g...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998752/ https://ncbi.nlm.nih.gov/pubmed/20964335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100346n |
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