Fragile site orthologs FHIT/FRA3B and Fhit/Fra14A2: Evolutionarily conserved but highly recombinogenic

Common fragile sites are regions that show elevated susceptibility to DNA damage, leading to alterations that can contribute to cancer development. FRA3B, located at chromosome region 3p14.2, is the most frequently expressed human common fragile site, and allelic losses at FRA3B have been observed i...

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Detaylı Bibliyografya
Asıl Yazarlar: Matsuyama, Ayumi, Shiraishi, Takeshi, Trapasso, Francesco, Kuroki, Tamotsu, Alder, Hansjuerg, Mori, Masaki, Huebner, Kay, Croce, Carlo M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC299872/
https://ncbi.nlm.nih.gov/pubmed/14630947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336256100
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