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The Met268Pro Mutation of Mouse TRPA1 Changes the Effect of Caffeine from Activation to Suppression
The transient receptor potential A1 channel (TRPA1) is activated by various compounds, including isothiocyanates, menthol, and cinnamaldehyde. The sensitivities of the rodent and human isoforms of TRPA1 to menthol and the cysteine-attacking compound CMP1 differ, and the molecular determinants for th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998636/ https://ncbi.nlm.nih.gov/pubmed/21112285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.014 |
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