A Combined Molecular Dynamics and Rapid Kinetics Approach to Identify Conserved Three-Dimensional Communication Networks in Elongation Factor Tu

Elongation factor (EF) Tu delivers aminoacyl-tRNAs to the actively translating bacterial ribosome in a GTP-hydrolysis-dependent process. Rapid recycling of EF-Tu, catalyzed by EF-Ts, is required for efficient protein synthesis in vivo. Here we report a combined theoretical and experimental approach...

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Detalhes bibliográficos
Main Authors: Wieden, Hans-Joachim, Mercier, Evan, Gray, John, Steed, Brett, Yawney, Davis
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998634/
https://ncbi.nlm.nih.gov/pubmed/21112298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.013
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