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A conserved P-loop anchor limits the structural dynamics that mediate nucleotide dissociation in EF-Tu

The phosphate-binding loop (P-loop) is a conserved sequence motif found in mononucleotide-binding proteins. Little is known about the structural dynamics of this region and its contribution to the observed nucleotide binding properties. Understanding the underlying design principles is of great inte...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mercier, Evan, Girodat, Dylan, Wieden, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286738/
https://ncbi.nlm.nih.gov/pubmed/25566871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07677
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