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Inactivation of the Elongation Factor Tu by Mosquitocidal Toxin-Catalyzed Mono-ADP-Ribosylation

The mosquitocidal toxin (MTX) produced by Bacillus sphaericus strain SSII-1 is an ∼97-kDa single-chain toxin which contains a 27-kDa enzyme domain harboring ADP-ribosyltransferase activity and a 70-kDa putative binding domain. Due to cytotoxicity toward bacterial cells, the 27-kDa enzyme fragment ca...

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Detalhes bibliográficos
Main Authors: Schirmer, Jörg, Wieden, Hans-Joachim, Rodnina, Marina V., Aktories, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126424/
https://ncbi.nlm.nih.gov/pubmed/12324336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.10.4894-4899.2002
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