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Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice

Clinical evidence indicates that fat is inversely proportional to bone mass in elderly obese women. However, it remains unclear whether obesity accelerates bone loss. In this report we present evidence that increased visceral fat leads to inflammation and subsequent bone loss in 12-month-old C57BL/6...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Halade, Ganesh V, Jamali, Amina El, Williams, Paul J, Fajardo, Roberto J, Fernandes, Gabriel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998554/
https://ncbi.nlm.nih.gov/pubmed/20923699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2010.09.014
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