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Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice

Clinical evidence indicates that fat is inversely proportional to bone mass in elderly obese women. However, it remains unclear whether obesity accelerates bone loss. In this report we present evidence that increased visceral fat leads to inflammation and subsequent bone loss in 12-month-old C57BL/6...

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Detalhes bibliográficos
Main Authors: Halade, Ganesh V, Jamali, Amina El, Williams, Paul J, Fajardo, Roberto J, Fernandes, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998554/
https://ncbi.nlm.nih.gov/pubmed/20923699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2010.09.014
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