Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis

BACKGROUND: Glucocorticoid (GC) resistance is frequently seen in acute lymphoblastic leukemia of T-cell lineage (T-ALL). In this study we investigate the potential and mechanism of using rapamycin to restore the sensitivity of GC-resistant T-ALL cells to dexamethasone (Dex) treatment. METHODS: Cell...

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Hlavní autoři: Gu, Ling, Zhou, Chenyan, Liu, Huajun, Gao, Ju, Li, Qiang, Mu, Dezhi, Ma, Zhigui
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998469/
https://ncbi.nlm.nih.gov/pubmed/21083937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-150
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