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Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis
BACKGROUND: Glucocorticoid (GC) resistance is frequently seen in acute lymphoblastic leukemia of T-cell lineage (T-ALL). In this study we investigate the potential and mechanism of using rapamycin to restore the sensitivity of GC-resistant T-ALL cells to dexamethasone (Dex) treatment. METHODS: Cell...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998469/ https://ncbi.nlm.nih.gov/pubmed/21083937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-150 |
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