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Enhanced Tumor Trafficking of GD2 Chimeric Antigen Receptor T Cells by Expression of the Chemokine Receptor CCR2b

For adoptive T cell therapy to be effective against solid tumors, tumor-specific T cells must be able to migrate to the tumor site. One requirement for efficient migration is that the effector cells express chemokine receptors that match the chemokines produced either by tumor or tumor-associated ce...

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Библиографические подробности
Главные авторы: Craddock, John A, Lu, An, Bear, Adham, Pule, Martin, Brenner, Malcolm K, Rooney, Cliona M, Foster, Aaron E
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998197/
https://ncbi.nlm.nih.gov/pubmed/20842059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181ee6675
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