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Reduction of the Ring Size of Radiolabeled Lactam Bridge-Cyclized Alpha-MSH Peptide Resulting in Enhanced Melanoma Uptake

The purpose of this study was to examine the profound effect of the ring size of the radiolabeled lactam bridge-cyclized α-melanocyte stimulating hormone (α-MSH) peptide on its melanoma targeting properties. METHODS: A novel cyclic α-MSH peptide, DOTA-Nle-CycMSH(hex) {1,4,7,10-Tetraazacyclododecane-...

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Autores principales: Guo, Haixun, Yang, Jianquan, Gallazzi, Fabio, Miao, Yubin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998183/
https://ncbi.nlm.nih.gov/pubmed/20150256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.071787
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