Identification and Functions of Amino Acid Residues in PotB and PotC Involved in Spermidine Uptake Activity

Amino acid residues on PotB and PotC involved in spermidine uptake were identified by random and site-directed mutagenesis. It was found that Trp(8), Tyr(43), Trp(100), Leu(110), and Tyr(261) in PotB and Trp(46), Asp(108), Glu(169), Ser(196), Asp(198), and Asp(199) in PotC were strongly involved in...

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Autori principali: Higashi, Kyohei, Sakamaki, Yoshiharu, Herai, Emiko, Demizu, Risa, Uemura, Takeshi, Saroj, Sunil D., Zenda, Risa, Terui, Yusuke, Nishimura, Kazuhiro, Toida, Toshihiko, Kashiwagi, Keiko, Igarashi, Kazuei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Membrane Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998158/
https://ncbi.nlm.nih.gov/pubmed/20937813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186536
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