Identification and Functions of Amino Acid Residues in PotB and PotC Involved in Spermidine Uptake Activity

Amino acid residues on PotB and PotC involved in spermidine uptake were identified by random and site-directed mutagenesis. It was found that Trp(8), Tyr(43), Trp(100), Leu(110), and Tyr(261) in PotB and Trp(46), Asp(108), Glu(169), Ser(196), Asp(198), and Asp(199) in PotC were strongly involved in...

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Dades bibliogràfiques
Autors principals: Higashi, Kyohei, Sakamaki, Yoshiharu, Herai, Emiko, Demizu, Risa, Uemura, Takeshi, Saroj, Sunil D., Zenda, Risa, Terui, Yusuke, Nishimura, Kazuhiro, Toida, Toshihiko, Kashiwagi, Keiko, Igarashi, Kazuei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998158/
https://ncbi.nlm.nih.gov/pubmed/20937813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.186536
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