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Regulation of the human GLUT4 gene promoter: Interaction between a transcriptional activator and myocyte enhancer factor 2A

The GLUT4 gene is subject to complex tissue-specific and metabolic regulation, with a profound impact on insulin-mediated glucose disposal. We have shown, by using transgenic mice, that the human GLUT4 promoter is regulated through the cooperative function of two distinct regulatory elements, domain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Knight, John B., Eyster, Craig A., Griesel, Beth A., Olson, Ann Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC299781/
https://ncbi.nlm.nih.gov/pubmed/14630949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2432756100
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