Acute Inhibition of Fatty Acid Import Inhibits GLUT4 Transcription in Adipose Tissue, but Not Skeletal or Cardiac Muscle Tissue, Partly Through Liver X Receptor (LXR) Signaling

OBJECTIVE: Insulin-mediated glucose uptake is highly sensitive to the levels of the facilitative GLUT protein GLUT4. Transcription of the GLUT4 gene is repressed in states of insulin deficiency and insulin resistance and can be induced by states of enhanced energy output, such as exercise. The cellu...

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Main Authors: Griesel, Beth A., Weems, Juston, Russell, Robert A., Abel, E. Dale, Humphries, Kenneth, Olson, Ann Louise
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Diabetes Association 2010
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844827/
https://ncbi.nlm.nih.gov/pubmed/20103707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1542
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