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Crystal structure of human α-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency
Human α-tocopherol (α-T) transfer protein (ATTP) plays a central role in vitamin E homeostasis, preventing degradation of α-T by routing this lipophilic molecule for secretion by hepatocytes. Mutations in the gene encoding ATTP have been shown to cause a severe deficiency in α-T, which results in a...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299775/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2136684100 |
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