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Crystal structure of human α-tocopherol transfer protein bound to its ligand: Implications for ataxia with vitamin E deficiency
Human α-tocopherol (α-T) transfer protein (ATTP) plays a central role in vitamin E homeostasis, preventing degradation of α-T by routing this lipophilic molecule for secretion by hepatocytes. Mutations in the gene encoding ATTP have been shown to cause a severe deficiency in α-T, which results in a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299775/ https://ncbi.nlm.nih.gov/pubmed/14657365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2136684100 |
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