RGS6, a Modulator of Parasympathetic Activation in Heart

RATIONALE: Parasympathetic regulation of heart rate is mediated by acetylcholine binding to G protein-coupled muscarinic M2 receptors, which activate heterotrimeric Gi/o proteins to promote GIRK channel activation. RGS proteins, which function to inactivate G proteins, are indispensable for normal p...

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Detalhes bibliográficos
Main Authors: Yang, Jianqi, Huang, Jie, Maity, Biswanath, Gao, Zhan, Lorca, Ramón A., Gudmundsson, Hjalti, Li, Jingdong, Stewart, Adele, Swaminathan, Paari Dominic, Ibeawuchi, Stella-Rita, Shepherd, Andrew, Chen, Ching-Kang, Kutschke, William, Mohler, Peter J., Mohapatra, Durga P., Anderson, Mark E., Fisher, Rory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997524/
https://ncbi.nlm.nih.gov/pubmed/20864673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.224220
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